The Kalow group engages in research at the interface of organic synthesis, polymer chemistry, and materials science through two distinct approaches: materials-inspired reaction discovery and reactivity-driven materials discovery. In the first, we develop new synthetic transformations that provide control over the molecular structure of 1- and 2-dimensional organic polymers. In the second, we use our knowledge of organic reactivity to tune the properties and functions of soft materials. These efforts enable the study of structure-property relationships and materials optimization for targeted applications, including optoelectronics and magnetooptics, catalysis, sensing, and biomaterials. Projects in the Kalow lab provide trainees with experience in method development, polymer synthesis, mechanistic analysis, and materials characterization and testing.
Accardo, J. V.; Kalow, J. A. “Reversibly tuning hydrogel stiffness through photocontrolled dynamic covalent crosslinks.” Chem. Sci., 2018, 9, 5987–5993.
Ishibashi, J. S. A.; Kalow, J. A. “Vitrimeric silicone elastomers enabled by dynamic Meldrum’s acid-derived crosslinks.” ACS Macro Lett., 2018, 7, 482–486.
Wang, X.; Kalow, J. A. “Rapid aqueous photouncaging by red light.” Org. Lett. 2018, 20, 1716–1719.
Zarzar, L. D.; Kalow, J. A.; He, X.; Walish, J. J.; Swager, T. M. “Optical Visualization and Quantification of Enzyme Activity using Dynamic Droplet Lenses.” Proc. Natl. Acad. Sci. 2017, 114, 3821–3825.
Kalow, J. A.; Swager, T. M. “Synthesis of Miktoarm Branched Conjugated Copolymers by ROMPing In and Out.” ACS Macro Lett. 2015, 4, 1229–1233.
Zarzar, L. D.; Sresht, V.; Sletten, E. M.; Kalow, J. A.; Blankschtein, D.; Swager, T. M. “Dynamic Reconfiguration of Complex Emulsions via Tunable Interfacial Tensions.” Nature 2015, 518, 520–524.
Kalow, J. A.; Doyle, A. G. “Mechanistic investigations of cooperative catalysis in the enantioselective fluorination of epoxides.” J. Am. Chem. Soc. 2011, 133, 16001–16012.
Kalow, J. A.; Doyle, A. G. “Enantioselective Ring Opening of Epoxides by Fluoride Anion Promoted by a Cooperative Dual-Catalyst System.” J. Am. Chem. Soc., 2010, 132, 3268–3269.
- 3M Non-Tenured Faculty Award, 2018
- Thieme Chemistry Journal Awardee, 2018
- Young Investigator Award, Air Force Office of Scientific Research, 2017
- Rising Stars in Chemistry Symposium, University of Chicago, 2015
- Ruth L. Kirschstein NIH NRSA Postdoctoral Fellowship, 2013–2016
- ACS Division of Organic Chemistry Graduate Fellowship, 2011–2012
- National Science Foundation Pre-Doctoral Fellowship, 2008–2011