Regan J. Thomson Associate Professor

Research Statement

Research within my group is focused at the frontiers of organic synthesis, both in terms of new reaction design, and in the synthesis of complex biologically active molecules. The rich interplay between these two sub-disciplines has been instrumental in driving forward the limits of our chemical knowledge and in defining new fields of research, such as chemical biology. Recent years have seen an explosion of scientific discoveries stemming from meaningful interdisciplinary, collaborative research: Organic synthesis has been, and will continue to be, at the heart of many of these endeavors.

Selected Publications

  • Total Synthesis of the Galbulimima Alkaloids Himandravine and GB17 using Biomimetic Diels–Alder Reactions of Double Diene Precursors, Larson, R. T.; Pemberton, R. P.; Franke, J. M.; Tantillo, D. J.; Thomson, R. J. J. Am. Chem. Soc. 2015, 137, 11197–11204
  • Investigations into Apopinene as a Biorenewable Monomer for Ring-Opening Metathesis Polymerization, Strick, B. J.; Delferro, M.; Geiger, F. M.; Thomson, R. J. ACS Sustainable Chem. Eng. 2015, 3, 1278–1281
  • Enantioselective Total Synthesis of (–)-Maoecrystal V, Zheng, C.; Dubovyk, I.; Lazarski, K. E.; Thomson, R. J. J. Am. Chem. Soc. 2014, 136, 17750–17756
  • Total Synthesis of the Isodon Diterpene Sculponeatin N, Moritz, B. J.; Mack, D. J.; Tong, L.; Thomson, R. J. Angew. Chem. Int. Ed. 2014, 53, 2988–2991
  • Climate-Relevant Physical Properties of Molecular Constituents for Isoprene-Derived Secondary Organic Aerosol Material, Upshur, M. A.;Strick, B. F.; McNeil, V. F.; Thomson, R. J.; Geiger, F. M. Atmos. Chem. Phys. 2014, 14, 10731–10740
  • Towards the Identification of Molecular Constituents Associated with the Surfaces of Isoprene-derived Secondary Organic Aerosol (SOA) Particles, Ebben, C. J.; Strick, B. F.;Upshur, M. A.; Chase, H. M.; Achtyl, J. L.; Thomson, R. J.; Geiger, F. M. Atmos. Chem. Phys. 2014, 14, 2303–2314

Selected Honors/Awards

  • Novartis Chemistry Lectureship (2015–2016)
  • Amgen Young Investigator (2010)
  • NSF CAREER Award (2009–2014)
  • Thieme Chemistry Journal Award (2008)