Elad Harel Assistant Professor

Research Statement

We are interested in understanding the connection between electronic structure and dynamics in complex, condensed-phase biomolecules. The three major areas of focus are on the use of light to control biological function, elucidating the role of the environment (e.g. solvent) on the function of proteins, and designing artificial systems that utilize coherent as well as incoherent processes to efficiently harvest and transport energy. We are developing advanced optical spectroscopic and imaging tools that in large part build on ideas from magnetic resonance. In particular, we are implementing novel correlation methods that can provide high-resolution maps of electronic structure at all relevant energy and temporal scales. Our research is highly interdisciplinary and crosses boundaries into biology, materials chemistry, mathematics, and engineering.

Selected Publications

1. E. Harel, P. D. Long, G. S. Engel, Single-shot ultrabroadband two-dimensional electronic spectroscopy of the light-harvesting complex LH2. Opt Lett 36, 1665 (May 1, 2011).

E. Harel, A. F. Fidler, G. S. Engel, Single-Shot Gradient-Assisted Photon Echo Electronic Spectroscopy. J Phys Chem A 115, 3787 (Apr 28, 2011).

G. Panitchayangkoon, D. Hayes, K. A. Fransted, J. R. Caram, E. Harel, J. Z. Wen, . . . G. S. Engel, Long-lived quantum coherence in photosynthetic complexes at physiological temperature. P Natl Acad Sci USA 107, 12766 (Jul 20, 2010).

E. Harel, A. F. Fidler, G. S. Engel, Real-time mapping of electronic structure with single-shot two-dimensional electronic spectroscopy. P Natl Acad Sci USA 107, 16444 (Sep 21, 2010).

E. Harel, Lab-on-a-chip detection by magnetic resonance methods. Prog Nucl Mag Res Sp 57, 293 (Oct, 2010).

A. F. Fidler, E. Harel, G. S. Engel, Dissecting Hidden Couplings Using Fifth-Order Three-Dimensional Electronic Spectroscopy. J Phys Chem Lett 1, 2876 (Oct 7, 2010).

V. S. Bajaj, J. Paulsen, E. Harel, A. Pines, Zooming In on Microscopic Flow by Remotely Detected MRI. Science 330, 1078 (Nov 19, 2010).

E. Harel, Magnetic resonance detection: spectroscopy and imaging of lab-on-a-chip. Lab Chip 9, 17 (2009).

S. J. Xu, E. Harel, D. J. Michalak, C. W. Crawford, D. Budker, A. Pines, Flow in Porous Metallic Materials: A Magnetic Resonance Imaging Study. J Magn Reson Imaging 28, 1299 (Nov, 2008).

E. Harel, L. Schroder, S. J. Xu, Novel Detection Schemes of Nuclear Magnetic Resonance and Magnetic Resonance Imaging: Applications from Analytical Chemistry to Molecular Sensors. Annu Rev Anal Chem 1, 133 (2008).

E. Harel, A. Pines, Spectrally resolved flow imaging of fluids inside a microfluidic chip with ultrahigh time resolution. J Magn Reson 193, 199 (Aug, 2008).

V. V. Telkki, C. Hilty, S. Garcia, E. Harel, A. Pines, Quantifying the diffusion of a fluid through membranes by double phase encoded remote detection magnetic resonance imaging. J Phys Chem B 111, 13929 (Dec 20, 2007).

E. Harel, C. Hilty, K. Koen, E. E. McDonnell, A. Pines, Time-of-flight flow imaging of two-component flow inside a microfluidic chip. Phys Rev Lett 98, (Jan 5, 2007).

J. Granwehr, E. Harel, C. Hilty, S. Garcia, L. Chavez, A. Pines, . . . Y. Q. Song, Dispersion measurements using time-of-flight remote detection MRI. Magn Reson Imaging 25, 449 (May, 2007).

E. Harel, J. Granwehr, J. A. Seeley, A. Pines, Multiphase imaging of gas flow in a nanoporous material using remote-detection NMR. Nat Mater 5, 321 (Apr, 2006).

E. Harel, H. Cho, A general numerical analysis of time-domain NQR experiments. J Magn Reson 183, 308 (Dec, 2006).

V. G. Stavros, E. Harel, S. R. Leone, The influence of intense control laser pulses on homodyne-detected rotational wave packet dynamics in O-2 by degenerate four-wave mixing. J Chem Phys 122, (Feb 8, 2005).

E. Harel, S. E. Meltzer, A. A. G. Requicha, M. E. Thompson, B. E. Koel, Fabrication of polystyrene latex nanostructures by nanomanipulation and thermal processing. Nano Lett 5, 2624 (Dec, 2005).

J. Granwehr, E. Harel, S. Han, S. Garcia, A. Pines, P. N. Sen, Y. Q. Song, Time-of-flight flow imaging using NMR remote detection. Phys Rev Lett 95, (Aug 12, 2005).

S. A. Maier, P. G. Kik, H. A. Atwater, S. Meltzer, E. Harel, B. E. Koel, A. A. G. Requicha, Local detection of electromagnetic energy transport below the diffraction limit in metal nanoparticle plasmon waveguides. Nat Mater 2, 229 (Apr, 2003).