Biological

Bioinorganic Chemistry

Electronic structure • elucidating bio-functionality • crystallography • diagnostics • therapeutics • bio-programmable materials • synthesis • metalloenzyme structure and function • model complexes • spectroscopy • biological proton transfer

Harris, Hoffman, Meade, Mirkin, O'Halloran, Rosenzweig

Chemical Biology

Molecular Mechanisms of Action, Design and Syntheses of Bioactive Small-Molecules • Neurodegenerative Diseases • Proteomics • Bioorganic Chemistry • Natural Product Bio- synthesis and Discovery • Cell Adhesion

Kelleher, Mrksich, Nguyen, Scheidt, Silverman, Stupp, Thomson

Total Synthesis & Method Development

Natural Product Synthesis • Alkaloids • Polyketides • Polycyclic Molecules • Organocatalysis • Asymmetric Catalysis • Organometallic Chemistry • Polymers • New Reaction Discovery and Development

Marks, Nguyen, Scheidt, Thomson

Biophysics

Electronic, magnetic, and structural properties of metalloenzymes using advanced electron spin resonance (EPR) and X-ray absorption/scattering techniques • Electronic structure and dynamics of photosynthetic proteins during energy and electron transfer • Utilizing quantum coherent effects in biohybrid materials • Lipid bilayer-nanoparticle interactions • protein folding

Chen, Geiger, Harel, Hoffman, Odom, Wasielewski

Theory & Computation

Fundamental treatment of coherence processes • Highly accurate wave function methods • Time-dependent dynamical studies • Control of chemical reactions • Structure and function of biological membranes

Olvera de la Cruz, Schatz, Seideman, Shiozaki, Szleifer